ABBaCo - Restauro Ambientale e Balneabilità del SIN Bagnoli-Coroglio

DIsCO - Diatom life cycles, molecular controls and contribution to ecosystem dynamics

EMSO MedIT - Project financed in the framework of PON R&C 2007-2013 - PAC Enhancement of public research infrastructures

GRASSMET - Climate change effects on seagrass secondary metabolism: ecological implications

HEATGRASS - Tolerance to HEAT stress induced by climate change in the seaGRASS Posidonia oceanica

HighGrass - High-CO₂ effects on seagrass photosynthetic ecophysiology

INBALANCE - INvertebrate-BActeriaL Associations as hotspots of benthic Nitrogen Cycling in Estuarine ecosystems

IRMA - Implementation and Remote Connection for Real Time Moniotoring of Marine Microorganisms - Funded by the Italian Ministry of University and Education (MIUR)

PALEOPARK - Seagrass palaeo-records as a tool for the evaluation, diagnosis and prognosis of the evolution of species, communities, and processes in Spanish insular National Parks

RECCAM - Seagrass Meadows resilience to global warming: an analysis based on responses at ecophysiological, population and ecosystem levels

OCEAN MEDICINES

PharmaDeep

PharmaSea

PON01_02093 Study of new technologies and technological platforms for the improvement of production processes of active pharmaceutical ingredients of industrial interest and search for new bioactive molecules from natural sources
Leader: Sanofi-Aventis S.p.A.

PON01_02782 New nanotechnological strategies for the development of drugs and diagnostic tools directed to circulating cancer cells (CTC).
Leader: Biogem S.c.a r.l

PON01_00117 Antigens and Adjuvants for Vaccines and Immunotherapy.
Leader: Novartis Vaccines & Diagnostics Ltd.

RESIGRASS - An holistic understanding of seagrass functioning and resilience to local-scale disturbances: from molecular to biogeographical scales

S&T MED - Financed by the ENPI CBC Mediterranean Sea Basin 2007/2013 Program of the European Union 

For more information and to book a visit: https://fondazionedohrn.it/home/dadom/

The Darwin-Dohrn Museum

Dedicated to the two giants of science and evolutionary biology, Charles Darwin and Anton Dohrn, the Darwin-Dohrn Museum - DaDoM – promotes the knowledge of the evolution of marine biodiversity.
Inside the DaDoM, visitors will voyage through the oceans through time in the footsteps of Darwin and Dohrn and many other scientists, discovering how organisms became adapted to all marine environments. In this journey through time and research, the public will understand the importance of the oceans in determining the conditions on the planet, will encounter the primordial forms of life that appeared in the oceans over 3 billion years ago, will discover evolutionary theories, and will encounter a series of fossils that show the evolution of forms and functions over the geological eras (walk through time).
Works of art, sculptures and historical biological samples will show how marine organisms move, feed, and reproduce, and the mechanisms that led to current life forms, in a gallery of biodiversity, from the simplest to the most complex organisms, to arrive at the multipurpose room of the DaDoM, housing a large skeleton of a sperm whale (beached along the Campania coasts and recovered by researchers), enriched by models of organisms that feed on the carcasses of these majestic giants of the sea when they arrive in the depths of the sea. The multipurpose room is dominated by a six-meter high wall that houses ten thousand preparations of animals from the Gulf of Naples, set up by the genius of Salvatore Lo Bianco and by those who followed his footsteps in the art of conservation.
The multipurpose room is designed to host thematic exhibits to explore topics of great scientific and popular interest, but also for scientific conferences and seminars, and is available to the cultural world for other initiatives of public interest, such as shows, concerts, exhibitions and film broadcasts. The museum itinerary also includes a journey through the studies and ancient maps of the Gulf of Naples, the discoveries of the over 20 Nobel laureates who conducted their studies in the SZN, up to the current research updated and exhibited month by month.
The Museum includes a large educational laboratory for students of all types and levels designed to carry out practical observation and study activities aimed at discovering the secrets of marine life. The upper floor of the building includes the staff offices, laboratories and organizations hosted by the Center. The Anton Dohrn Zoological Station has returned to the citizens of Naples, Campania and the whole country an asset of the city in its full fruition. This objective will also be extended to the outside of the building, making the garden of the Museum a place of knowledge in the open air. In fact, the garden hosts two scientific submersibles made available by the MareAmico Cultural Association and which have also been used for the exploration of the deep sea environments of the Mediterranean.
Depending on specific needs, the rear lawn or the roof terrace will finally host an open-air summer cinema for documentaries on the sea and for an international competition on scientific cinema and marine documentaries.

Scientific, Educational and Cultural Center in the heart of the city

With the aim of strengthening the so-called "third mission", i.e. the activities of dissemination of scientific discoveries, as well as the opening of research facilities to citizens, with their direct involvement, the Darwin-Dohrn Museum offers opportunities for scientific and educational collaborations, training of teachers and specialists in the sector, educational workshops, cultural meetings, and guided tours for citizens and tourists.
The Museum was inaugurated on December 9, 2021 but its layout will be continuously enriched with new material and new initiatives.

ABBACO SZN - ISS

ABBACO SZN - Conisma 

ABBACO SZN - Università degli Studi di Napoli Federico II

ABBACO SZN - DICEA

ABBACO SZN - ENEA

ABBACO SZN - IAMC

ABBACO SZN - INGV

ABBACO SZN - ISAC

ABBACO SZN - Università degli Studi di Napoli "Parthenope"

ABBACO SZN - Università degli Studi della Campania "Luigi Vanvitelli"

ABBACO SZN - Università Politecnica delle Marche

Responsible: Adrianna Ianora

Activities

The Biotechnology Laboratory is a multidisciplinary lab that uses and develops different approaches dedicated to the study of marine drug discovery. Research activities include sampling, isolation and maintenance of marine species of biotechnological interest (especially microalgae), preparation of chemical extracts, testing the potential bioactivity at the gene and protein levels of extracts on human cells and model marine organisms.

Experimental Systems

• Molecular and chemical facilities applied to marine biotechnology.
• Human cell culture chambers (biological hood type 1, incubator for human cells, microscopes).
• Rooms for microalgal growth.
• Room with 2 Bioreactors.

Analysis

• Isolation and maintenance of microalgae for potential biotechnological applications.
• Cultivation of microalgae at the small (flasks), medium (10L carboys) and large scale (photobioreactors 100 L).
• Genotyping of new species by DNA sequencing.
• Bioassays testing biological activity of extracts, fractions and pure compounds on marine model species and human cell lines.
• Antiproliferative and clonogenic bioassays against aggressive tumor cell lines.
• Antioxidant and anti-inflammatory bioassays on normal cell lines.
• Cellular senescence (anti-aging)bioassays.
• Chronic human diseases (diabetes, Alzheimer's, Crohn's disease) bioassays.
• Molecular studies at the gene and protein levels to identify specific pathways activated by bioactive compounds on human cells (retroviral transfection, PCR array, immunoblot, ELISA).
• Transcriptome analysis of microalgal species.

Equipment

• Basic instrumentation for molecular biology and protein analysis (PCR, centrifuges, electrophoresis apparatus, transilluminator, thermostatic baths, spectrophotometer, pH meter, transblot).
• Biological Type 2 hood for micralgal cultures.
• Chemical hood.
• Microscopes.
• 2 photobioreactors (100 L).