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caccavale filomenaPhD Student SZN-OU
Section BEOM

Tel. +39 081 5833255
Fax: +39 081 7641355
e-mail filomena.caccavale(at)szn.it

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Research interests

Amphioxus is a benthic filter feeder animal that lives in constant undercurrents areas. Among the several amphioxus species, the Mediterranean ones is Branchiostoma lanceolatum that is also present in few areas in the Gulf of Naples. Amphioxus is a member of the cephalochordate subphylum that represents the most basally divergent lineage of chordates. It shows all the prototypic characteristics of the chordate group and its genome is non-duplicated unlike that of vertebrates. Thus, the morphological and genomic simplicity of amphioxus, together with its key phylogenetic position, make it an useful animal model for evolutionary and developmental studies. I’m interested in the study of Nitric Oxide Synthases (NOS), a family of enzymes involved in the production of the gaseous and high reactive molecule Nitric Oxide (NO). It is known that NOS and NO are involved in a wide spectrum of physiological processes both in vertebrates and invertebrates. Aims of project include the study of the expression profile of amphioxus NOS genes, NO localization and functions, NOS genes regulation.

Journal Papers

Vassalli QA, Caccavale F, Avagnano S, Murolo A, Guerriero G, Fucci L, Ausió J, Piscopo M. (2015). New insights into protamine-like component organization in Mytilus galloprovincialis' sperm chromatin. DNA Cell Biol. 34(3):162-9

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