Researchers and Technologists

Maria Ina Arnone

Maria Ina Arnone

Research interests: Evolution and development at the gene regulatory network (GRN) and cell type levels.  Current projects in the lab are: Mesenchyme formation and muscle specification; A gene regulatory network involved in patterning of the gut; Sensory cells in the sea urchin adult and larva.

Current projects:

Gene Regulatory Networks for Development

• Structure and evolution of the gene regulatory networks that control organogenesis
• Sensory cells in the sea urchin adult and larva
• Evolution and development of nervous system of deuterostomes

Selected Publications:

Ullrich-Lüter E, Dupont S, Arboleda E, Hausen H and Arnone MI. A Unique System of Photoreceptors in Sea Urchin Tube Feet Proc Natl Acad Sci U S A. (2011) 108: 8367-72.

Cole, AG, Rizzo F, Fernandez-Serra M, Martinez  P, and Arnone MI.  ParaHox genes coordinate to pattern the posterior endoderm.  Development  (2009) 136, 541-9.

Cole AG, Arnone MI.  Fluorescent in situ hybridization reveals multiple expression domains for SpBrn1/2/4 and identifies a unique ectodermal cell type that co-expresses the ParaHox gene SpLox.  Gene Expr. Patterns (2009) 9, 324-8.

Arnone MI, Rizzo F, Annunziata R, Cameron RA, Peterson KJ, Martinez P. Genetic organization and embryonic expression of the ParaHox genes in the sea urchin S. purpuratus: Insights into the relationship between clustering and colinearity. Dev. Biol. (2006) 300, 63-73.

Rizzo F, Fernandez-Serra M, Squarzoni P, Archimandritis A, Arnone MI.  Identification and developmental expression of the ets gene family in the sea urchin (Strongylocentrotus purpuratus).  Dev. Biol. (2006) 300, 35-48.

Raible F, Tessmar-Raible K, Arboleda E, Kaller T, Bork P, Arendt D, Arnone MI.  Opsins and clusters of sensory G-protein-coupled receptors in the sea urchin genome. Dev. Biol. (2006) 300, 461-475.

Sea Urchin Genome Sequencing Consortium; Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA… et al The genome of the sea urchin Strongylocentrotus purpuratus.  Science (2006) 314, 941-952. 

Fernandez-Serra M, Consales C, Livigni A and Arnone MI. Role of the ERK-mediated signaling pathway in mesenchyme formation and differentiation in the sea urchin embryo.  Dev. Biol. (2004) 268, 384-402. 

E.H. Davidson, J.P. Rast, P. Oliveri, A. Ransick, C. Celestani, C-H Yuh, T. Minokawa, G. Amore, V. Hinman, C. Arenas-Mena, O. Otim, C.T. Brown, C. Livi, P. Lee, R. Revilla, A. Rust, Z. Pan, M. Schilstra, P.J.C. Clarke, M.I. Arnone, L. Rowen, R.A. Cameron, D.R. McClay, L. Hood and H. Bolouri. A genomic regulatory network for development. Science (2002) 295, 1669-1678.

Arnone M.I.  Bringing order to organogenesis.  Nat. Genet. (2002) 30, 348-350.

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